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Fig. 1D 49-year-old woman who had undergone ipsilateral lumpectomy yielding
ductal carcinoma in situ (DCIS) 3 years earlier. Sagittal image from
T1-weighted 3D fat-suppressed fast spoiled gradient-echo sequence (17/2.4;
flip angle, 35°) obtained after IV contrast injection on day of MRI-guided
vacuum-assisted biopsy. Nipple and susceptibility artifacts (black
arrow) serve as landmarks to show that biopsy obturator was placed at
site of suspicious enhancement (white arrow). More background
enhancement is evident on biopsy day because patient underwent imaging in
different phase of menstrual cycle. Histologic examination of MRI
vacuum-assisted breast biopsy specimens revealed foci of marked atypical
ductal hyperplasia involving florid sclerosing adenosis. Histologic
examination after surgical excision showed DCIS, solid and cribriform types,
intermediate to high nuclear grade, apocrine cytologic features, and minimal
necrosis, mostly involving sclerosing adenosis.