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Fig. 2 Axial T2-weighted MR image through midgland of prostate in
68-year-old man with prostate-specific antigen value of 6.4 ng/mL and negative
findings on one prior biopsy. No focal T2 signal abnormality is visible, but
two (asterisks) of four highlighted MR spectroscopic imaging (MRSI)
voxels show moderate choline elevation (spectral peaks labeled 1 for choline,
2 for creatine, and 3 for citrate), which is suspicious for malignancy. Cancer
was found in right hemigland on subsequent biopsy. Although addition of MRSI
to MRI was helpful in diagnosis of prostate cancer in this case, our study
showed no overall incremental benefit.