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Fig. 2C —Stage pT3 squamous cell carcinoma (SCC) of right distal ureter. Photograph of pathologic specimen shows SCC (white arrowheads) and thickening of both muscularis and adventitia (white arrows) due to marked proliferation of fibrous tissue that is partially invaded by SCC. Necrotic change is also depicted in tumor (curved arrow). Tumor invaded into periureteral fat tissue through area in thickened muscularis, and adventitia (black arrow) was disrupted. Intensely enhancing rim corresponds to thickened muscularis and adventitia due to proliferation of fibrous tissue. Relatively moderate enhancing ill-defined mass corresponds to SCC. Poorly enhancing region corresponds to necrotic tissue in tumor. (H and E, loupe)