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Fig. 4 —Graph shows linear regression relation (percentage change in size = 109.11 - [0.05 x ADC150-500]; R² = 0.34; p = 0.03) with 95% predictor intervals between percentage reduction in size and mean pretreatment apparent diffusion coefficient for images with b values of 150 and 500 s/mm² (ADC150-500). Responding lesions (black circles) are distributed mainly in upper left quadrant and nonresponding lesions (white circles) in lower right quadrant. Positive values on y-axis indicate tumor regression, negative values indicate tumor growth. Line through value of 30% on y-axis segregates responding from nonresponding lesions. Line through value of 1.69 x 10^-3 mm²/s on x-axis indicates likelihood of tumor response.