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Fig. 5A —Box-and-whisker plots show pretreatment (white) and posttreatment (gray) mean apparent diffusion coefficients (ADCs) for images with b values of 0, 150, and 500 s/mm² (ADC0-500) and those for images with b values of 150 and 500 s/mm² (ADC150-500). Responding metastatic lesions. Increase in median of mean ADC0-500 and mean ADC150-500 among responding metastatic lesions after chemotherapy is evident. Circles indicate outliers.