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Fig. 1B —Pretreatment MR images in 44-year-old woman with newly diagnosed Gaucher's disease. Sagittal T1-weighted (A) and T2-weighted (B) images of lumbar spine show bone marrow of lower signal intensity than disk and presacral fat. Score for signal intensity was 4 and for distribution was 3 since fat around basivertebral veins was replaced. Lumbar bone marrow burden (BMB) score was thus 7.