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Figure 13


Fig. 6 Diffusion-weighted imaging in liver. Graph shows signal attenuation of normal liver with increasing b values (thin dashed line). Note there is initial rapid attenuation of signal intensity with small increase in b value from zero. This is due to nulling of signal contribution from capillary perfusion. Slope of line (thick dashed line) fitted through all b values describes apparent diffusion coefficient (ADC). However, slope of line (thick solid line) fitted through only higher b values (e.g., 150–500 mm2/s) can be used to describe perfusion-insensitive ADC. Error bars show 95% CI of pixel values.