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Fig. 4 —70-year-old woman with painless obstructive jaundice. Axial contrast-enhanced CT image shows hourglass configuration of gallbladder and suggestion of intramural diverticula in fundus (arrow). Histopathologic analysis did not show macroscopic evidence of malignant tumor of gallbladder, but foci of malignant cells were found in gallbladder wall at microscopy and were considered indicative of primary gallbladder cancer.