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Fig. 4A —52-year-old woman with acute pulmonary thromboembolism (PTE). R = right. CT scan (left) shows wedge-shaped area of low attenuation in right lung base (left image, arrow). Deep-inspiratory breath-hold (DIBrH) SPECT enhances perfusion defects compared with non-breath-hold SPECT, with expansion of several defects (center image, arrows). Image set of transaxial DIBrH SPECT, SPECT/CT fusion, and CT (right images) shows excellent matching between perfusion defects and low CT attenuation.