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Fig. 3A —Missed cancers at index endoscopy. Prone axial CT colonography image in 65-year-old man shows large polyp in sigmoid colon (arrow) that was detected by both reviewers using every combination of slice thickness and primary search method. Histopathology showed 1.3-cm invasive adenocarcinoma invading submucosa but not muscularis propria with positive lymph nodes.