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Fig. 2E —MRI of SCCVII (squamous cell carcinoma) tumors. From left to right, images are unenhanced T1-weighted, contrast-enhanced T1-weighted, and T2-weighted. Images after application of continuous-wave HIFU. Unenhanced T1-weighted image is D; no contrast material uptake (arrow) on contrast-enhanced T1-weighted image (E) was seen as sign of devascularization. On T2-weighted image (F), treated tissue shows higher signal intensity (arrow).