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Fig. 2B —Organ-confined prostate cancer (TNM stage T2) in 73-year-old man. Axial T2-weighted MR image (A) shows prostate carcinoma presenting as focal low-signal area in peripheral zone on left (arrow) and having isointense signal on T1-weighted image (B). Peripheral zone (arrowheads) is normally high signal and central zone (diamond) is often heterogeneous because of benign prostatic hyperplasia on T2-weighted sequences. Note that the transition and central zones cannot be distinguished and are termed central zone or central gland on MR images. Central gland and peripheral zone are isointense on T1-weighted sequences.