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Fig. 2E —63-year-old asymptomatic woman with family history of breast cancer who had abnormal right breast MRI performed at outside facility. Sagittal T1-weighted MR image after needle localization shows signal void from placement of three MRI-compatible bracketing wires (arrows) to assist surgeon in wide excision. Histologic analysis revealed extensive multifocal ductal carcinoma in situ (DCIS), micropapillary, flat (clinging), and focally solid types, intermediate nuclear grade, arising in background of atypical ductal hyperplasia, with multiple positive margins. Mastectomy was performed, yielding residual DCIS with negative sentinel nodes.