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Fig. 2B —20-year-old man with neurofibromatosis type 1 who presented with enlarging calf mass. Coronal FDG PET image shows increased FDG uptake in large plexiform neurofibroma with two foci of increased uptake (standardized uptake value = 4.1) (arrows) that are suspicious for malignant transformation. Mass was resected and foci of malignant transformation were found.