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Figure 6


Fig. 2C —58-year-old man with 9-mm solid nodule with irregular margins on surveillance CT scan obtained 15 months after baseline CT (cancer # 2). For CT examinations, t, t–1, and t–2, respectively, designate current, most recent prior examination, and second most recent prior examination. Numbers marked with C are automatically generated by computer-aided detection (CAD) system and indicate presence of nodule candidate. Image from second follow-up CT at time t (119 days) shows slight increase in lesion size. Between B and C, CAD calculated volumetric growth, and doubling time was 48.6% and 208 days, compatible with malignant lesion (biopsy-proven adenocarcinoma).