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Fig. 4B —38-year-old man with HIV infection, fever, and generalized lymphadenopathy. Pleural biopsy showed human herpesvirus 8 and Epstein-Barr virus in lymphoma cells, which is consistent with primary effusion lymphoma. Axial chest CT images show large pleural (arrows, C) and chest wall mass with associated pleural effusion. Note also pronounced right axillary lymphadenopathy.