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Fig. 4C —75-year-old man with liver cirrhosis related to hepatitis B virus infection and with high-grade dysplastic nodule. Contrast-enhanced Coherent Contrast Imaging (CCI; Acuson Sequoia, Siemens Medical Solutions) oblique sonograms show nodule (arrow) has homogeneous hypervascular appearance during arterial phase (B) and appears isovascular during portal venous phase (C) 130 seconds after microbubble injection.