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Fig. 5B —75-year-old man with liver cirrhosis related to hepatitis B virus infection and with regenerative nodule. Contrast-enhanced Coherent Contrast Imaging (CCI; Acuson Sequoia, Siemens Medical Solutions) longitudinal sonograms show nodule (arrow) is 2.5 cm in diameter and appears hypovascular during arterial phase (A) 25 seconds after microbubble injection. Lesion became isovascular in portal venous phase (B) 140 seconds after microbubble injection and is isovascular in portal venous phase 150 seconds after injection.