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Fig. 2D —Patient with gastrointestinal stromal tumor (GIST) who did not respond to imatinib mesylate treatment. Transaxial CT images corresponding to A and B before (C) and 1 month after (D) initiation of imatinib mesylate therapy show two tumors (arrows) on far right side of these images that had tripled in size according to CT bidimensional measurements in 1 month.