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Fig. 1 —Comparison of pathologic results of 2,420 sonographically guided 14-gauge core needle biopsies with gold standard. Gold standard results are from surgical excision (616 cases), vacuum biopsy (i.e., sonographically guided directed vacuum-assisted core biopsy) (195 cases), or long-term imaging follow-up (353 cases). Note that remaining 1,256 lesions were confirmed malignant after sonographically guided core needle biopsy. A = agreement cells, U = underestimate cells, M = misses, ICA = invasive cancer, DCIS = ductal carcinoma in situ, HR = high-risk lesion, B9 = benign lesion. (Adapted from Burbank F, Parker SH. Methods for analysis of one-step breast biopsy programs. Breast J 1998; 4:307-319 [18])