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Fig. 1 —Flow diagram depicts manner in which patients were selected. Top
three boxes describe procedures completed for clinical care. Bottom five boxes
describe procedures completed for research study. Inclusion criteria were
double-contrast MRI performed, cirrhosis histologically confirmed, and liver
explant examined after double-contrast MRI examination. Exclusion criteria
were ablative therapy before study MRI and liver explant performed more than
12 months after MRI in patients in whom explant had positive results for
hepatocellular carcinoma (HCC). For patients in whom explant had negative
results for HCC, MRI-explant interval greater than 12 months was acceptable,
and such patients were not excluded.