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Fig. 1 —Graph shows initial and follow-up volumes in hippocampus with abnormal signal intensity on initial imaging (patients 1–7 in Table 1). For patient 2, solely hippocampus with most abnormal signal intensity is depicted. Children with solely normal hippocampal signal intensity (patients 8–11) are not included in this graph. Each child's hippocampus is denoted by single color different from other children; numbers in graph correlate to patient numbers in Table 1. Graph compares hippocampal volume change over time with growth curve of normal hippocampal volumes (black line) generated from normal MR scans of 30 children of various ages who had no history of developmental delay or seizures. Varying degrees of hippocampal volume decrease are seen in six of seven children. Furthermore, degree of volume loss is most marked in patients 1–3, who had moderate or severe signal abnormality within hippocampus represented here.