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Fig. 7B —Sodium (²³Na) MRI. In vivo multiple-quantum transfer coherence filtered ²³Na images of control (B) and carbon tetrachloride (CCl₄)-treated (C) rats. Treated rats develop chemical hepatitis similar to nonalcoholic steatohepatitis and show hepatic hyperintensity (arrowhead, C) not seen in untreated rats (arrow denoting site of liver, B) in multiple-quantum transfer coherence filtering image due to increase in intracellular sodium (Nai⁺). Sodium-23 techniques yield MR images as well as MR spectroscopy.