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Fig. 4A —Chemical shift MRI detection of hepatic fat in 56-year-old man with nonalcoholic steatohepatitis. Liver appears diffusely hypointense on out-of-phase gradient-echo sequence (TR/TE, 130/2.2; flip angle, 70°) (B) compared with in-phase sequence (130/4.9; flip angle, 70°) (A), indicating presence of fat.