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Fig. 6B —5-year-old boy with Proteus syndrome and megalencephaly. (Courtesy of Parmar H, University of Michigan Health System, Ann Arbor, MI) Axial T2-weighted fast spin-echo MR image (3,200/102; slice thickness, 6 mm) through level of cerebral hemispheres reveals enlargement of right cerebrum with associated abnormal cortical sulcation and gyration (arrowheads).