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Fig. 4B —17-year-old girl with glioblastoma multiforme. Corresponding axial ¹⁸F-FDG PET image shows moderate FDG accumulation (arrow). Parameters of this patient were average standard uptake value (SUV_avg), 11.25; maximum SUV (SUV_max), 13.73; average tumor-to-cortex activity ratio (T/C_avg), 1.84; ratio of count of maximum pixels in tumor to average count per pixel in cortex (T/C_max), 2.25; average tumor-to-white matter activity ratio (T/WM_avg), 3.84; and ratio of count of maximum pixels in tumor to average count per pixel in white matter (T/WM_max),4.68.