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Fig. 1A —70-year-old woman with recent (< 6 months previously)
diagnosis of atypical lobular hyperplasia by stereotactic biopsy of right
breast calcifications. Bilateral MRI was performed to rule out occult
malignancy. In this and all subsequent figures, sagittal image is from first
run of dynamic contrast-enhanced series, and axial image is from delayed
contrast-enhanced series. Sagittal (A) and axial (B) T1-weighted
fat-suppressed 3D fast spoiled gradient-recalled echo images after contrast
injection show 1.5-cm area of ductal and clumped enhancement (arrows)
in contralateral breast, with persistent enhancement kinetics and no
mammographic correlate. MRI-directed core biopsy followed by excision revealed
ductal carcinoma in situ, cribriform and solid types, intermediate nuclear
grade, with central necrosis.