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Fig. 1D —54-year-old woman with neuroendocrine carcinoma of small bowel. Both observers correctly identified 12-mm metastatic lesion (short arrow) on all images and detected 4- and 5-mm metastatic lesions (long arrows, D and E) only with diffusion-weighted single-shot echo-planar sequence. Small cyst (arrowhead) has markedly high signal intensity in D that fades out in E, whereas metastatic lesions retain their high signal intensity. Cyst has high apparent diffusion coefficient (ADC) and is clearly visible in F, whereas metastatic lesions have low ADC similar to that of hepatic parenchyma. Diffusion-weighted respiration-triggered single-shot echo-planar MR image, b = 50 s/mm².