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American Journal of Roentgenology, Vol 100, 202-207, Copyright © 1967 by American Roentgen Ray Society


INTRATHORACIC NEUROBLASTOMA

OLE EKLÖF M.D.1 and CHARLES A. GOODING M.D.2

1 From the Department of Diagnostic Radiology, Children's Clinic (Director: Docent UlfRudhe), Karolinska Sjukhuset
2 Philip H. Cook Fellow in Radiology, Harvard Medical School, Boston, Massachusetts

Collected material from several Swedish medical centers has produced 100 cases, histologically documented as neuroblastoma, with clinical histories anti roentgenograms available. Of these, there were 13 cases of primary intrathoracic origin of the tumor and 12 cases of secondary spread to the thoracic mediastinum by contiguity or metastatic means. Roentgenologic evaluation has shown that calcification is uncommon in the intrathoracic cases of primary origin, that it is not seen at all in the cases of secondary mediastinal deposits, and, very importantly, that what clinically presents as a primary intrathoracic mass may in reality represent a metastatic focus. Five of the 13 cases of primary intrathoracic neuroblastoma have been cured and I case had been operated upon too recently to determine the prognosis. No patient with both thoracic anti abdominal involvement by this tumor has been cured.


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