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American Journal of Roentgenology, Vol 103, 44-52, Copyright © 1968 by American Roentgen Ray Society

RADIOTHERAPY IN THE MANAGEMENT OF CRANIOPHARYNGIOMAS

FURTHER EXPERIENCES AND LATE RESULTS

SIMON KRAMER M.D.1, MARTHA SOUTHARD M.D.1, and CARL M. MANSFIELD M.D.1

1 From the Jefferson Medical College Hospital, Philadelphia, Pennsylvania

The results of treatment in 12 children and 14 adults with craniopharyngiomas are reported.

Of 10 patients treated by a planned surgical-radiotherapeutic approach (Ist Series) I adult and 6 children are alive and well 13frac12 to 15 years after treatment without evidence of recurrence or brain damage. Three adults have died of intercurrent disease at 2, Jo and 14 years after treatment.

Of 16 patients irradiated more recently (2nd Series) 6 were referred only after recurrence following surgical treatment. Four of 6 children (I recurrent tumor) and 7 of 10 adults (4 recurrent tumors) are alive and well 6 months to 8 years and 10 months after treatment without evidence of recurrence or brain damage.

Radiation therapy after surgical biopsy and cyst evacuation appears to offer the best chance of long-term control for craniopharyngiomas.


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N. Karavitaki, S. Cudlip, C. B. T. Adams, and J. A. H. Wass
Craniopharyngiomas
Endocr. Rev., June 1, 2006; 27(4): 371 - 397.
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Copyright © 1968 by the American Roentgen Ray Society.