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American Journal of Roentgenology, Vol 103, 863-870, Copyright © 1968 by American Roentgen Ray Society

DEPTH DOSE STUDIES IN ELECTRON BEAM THERAPY

EFFECTS ON ANAGEN MOUSE HAIRS

LAWRENCE H. LANZL PH.D.1, FREDERICK D. MALKINSON M.D., D.M.D. 2, and THOMAS J. AHRENS 3

1 From the Department of Radiology, and the Argonne Cancer Research Hospital, The University of Chicago, Chicago, Illinois
2 From the Department of Medicine (Dermatology), The University of Chicago, Chicago, Illinois
3 The Argonne Cancer Research Hospital, The University of Chicago, Chicago, Illinois

Detailed physical and biologic depth dose studies for a 20 mev. scanning electron beam are reported to further elucidate the clinical impression of "skin sparing" effect observed when electron beams are used for cancer therapy. The biologic dosimeter used was the damaging effect on anagen mouse hair by electron irradiation. There is substantial agreement of the "surface-to-plateau" dose ratio between the physical and biologic dosimeters utilized here. Even though the linear energy transfer (LET) cannot be expected to be identical at the surface as compared with the depth, this difference has not produced a significantly different RBE at the two positions for the biologic indicator used.


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Copyright © 1968 by the American Roentgen Ray Society.