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American Journal of Roentgenology, Vol 104, 145-149, Copyright © 1968 by American Roentgen Ray Society

TISSUE AND TUMOR CONCENTRATIONS OF TECHNETIUM 99m AS PERTECHNETATE

FRED S. MISHKIN M.D.1 and ISAAC C. REESE M.S.2

1 Assistant Professor of Radiology, Indiana University Medical Center, Indianapolis, Indiana
2 From the Department of Radiology, Section of Radioisotopes, Indiana University Medical Center, Indianapolis, Indiana

Measurement of tissue levels of technetium 99m were performed in patients who had a meningioma, chronic subdural hematoma and fibrous dysplasia of the skull.

[See table in the PDF file]

[See figure in the PDF file]

Technetium 99m is shown to concentrate in the brain tumor to a level twice that of blood.

Technetium 99m is not specific for brain tumors, and concentrates in lesions of bone, but to a much less degree than strontium 85. Thus it is worthwhile repeating a positive technetium 99m scan with strontium 85 in a patient suspected of having a bone lesion, in order to distinguish brain from bone lesions.

The peripheral rim of activity seen in the technetium 99m brain scan can be remarkably diminished by external pressure, and is thought to be accounted for in great part by the subcutaneous tissues, as well as the great venous sinuses of the dura.


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Copyright © 1968 by the American Roentgen Ray Society.