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American Journal of Roentgenology, Vol 104, 632-640, Copyright © 1968 by American Roentgen Ray Society

REFLUX PANCREATOGRAPHY

AN EVALUATION OF CONTRAST AGENTS FOR STUDYING THE PANCREAS

ROBERT L. WALDRON II M.D.1

1 From the Department of Radiology, Columbia-Presbyterian Medical Center, New York, New York

Animal experiments were performed to compare several types of contrast materials using conditions which simulate those employed in reflux pancreatography. The water soluble agent, sodium diatrizoate, was markedly superior to barium and oily contrast agents. It was observed that sodium diatrizoate passes through the pancreas rapidly and that a pyelogram results. It is postulated that a ductovenous pathway is utilized keeping contact of the water soluble contrast material with acinar cells to a minimum while allowing sufficient pancreatic opacification for diagnostic study. Reflux pancreatography with sodium diatrizoate can be advocated in humans on the basis of safety in animal experiments.


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Copyright © 1968 by the American Roentgen Ray Society.