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1 From the Department of Radiation Physics and the Department of Radiotherapy, Boston University Medical Center, Boston, Massachusetts
In the radium treatment of endometrial carcinoma using Heyman's packing technique, variations in shape and size of malignant uteri become very important in evaluation of the dose delivered to uterine walls and the adjacent structures. Because of these difficulties, an unsatisfactory method of stating dosage in milligram-hours of radium has been retained in gynelogic curie therapy.
An experimental program to determine the distribution of radiation along the periphery of the uterine wall as well as to structures of anatomic importance was recently completed. Multiple measurements were performed in different sizes of uterine models using Sievert miniature ionization chambers, lithium fluoride dosimeters and slow films. A limited computer program was written to check the pattern of experimental measurements. The results were satisfactory and an extensive computer program was started to develop a system of complete radium dosage patterns for uterine cavities of different size and shape and their associated radium content.
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