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American Journal of Roentgenology, Vol 105, 529-535, Copyright © 1969 by American Roentgen Ray Society


RADIATION INDUCED NEOPLASIA FOLLOWING EXTERNAL BEAM THERAPY FOR CHILDREN WITH RETINOBLASTOMA

ROBERT H. SAGERMAN M.D.1, J. ROBERT CASSADY M.D.1, PATRICIA TRETTER M.D.1, and ROBERT M. ELLSWORTH M.D.2

1 From the Department of Radiology, Division of Radiotherapy of the Columbia-Presbyterian Medical Center, New York, New York
2 From the Institute of Ophthalmology, Retinoblastoma Clinic of the Columbia-Presbyterian Medical Center, New York, New York

Radiation induced neoplasia was assessed in a uniform population—children treated with irradiation for retinoblastoma.

The incidence of radiation induced neoplasia varied with dose, and is estimated to be approximately 1.5 per cent with current techniques (megavoltage, 3,500 rads in 18-20 days, treatment three times a week).

There was no direct correlation of dose with latent period.


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