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American Journal of Roentgenology, Vol 106, 604-613, Copyright © 1969 by American Roentgen Ray Society

ROENTGEN FINDINGS IN EXTRAMEDULLARY HEMATOPOIESIS

PAUL ROSS M.B., B.S.1 and WENDE LOGAN M.D.1

1 From the Department of Radiology, Strong Memorial Hospital, Rochester, New York

1. A definite roentgenographic diagnosis of thoracic extramedullary hematopoiesis can be made if the patient has:

(a) a lobulated or rounded soft tissue density in the posterior mediastinum without rib erosion,

(b) roentgen changes in the bones of chronic hemolytic anemia or myelofibrosis,

(c) an enlarged spleen or a history of splenectomy, and

(d) a history of chronic anemia.

2. Extramedullary hematopoietic tissue may compress the spinal cord. Radiation therapy is effective.

3. A notched appearance of the expanded ribs seen only in patients with thalassemia is described.

4. Possibly peripelvic extramedullary hematopoietic tissue may mimic renal fibrolipomatosis.


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