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American Journal of Roentgenology, Vol 107, 702-710, Copyright © 1969 by American Roentgen Ray Society

SICKLE CELL DISEASE

THE ROENTGENOLOGIC MANIFESTATIONS OF URINARY TRACT ABNORMALITIES IN ADULTS

S. I. MARGULIES M.D.1 and SANFORD D. MINKIN M.D.1

1 From the Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland

The population at The Johns Hopkins Hospital was screened for patients with proven SS disease who were 15 years of age or older.

One hundred and twelve adults with electrophoretically proven hemoglobin SS disease were found. In this group 17 had intravenous pyelography and the roentgenographic findings in these patients were studied.

Isosthenuria causing poor visualization of the renal collecting systems, pyelonephritis causing caliectasis and loss of renal cortex, and hematuria causing transient nonvisualization of a renal collecting system or filling defects within the renal papilla were identified. No roentgenographic cases of unequivocal renal papillary necrosis were found.

No positive correlation between the patients' symptoms, or lack of symptoms, and the roentgenographic findings could be made.

It is felt that the radiologist should be aware of the renal changes that occur in sickle cell disease and, in view of the poor renal concentration, should recommend intravenous drip pyelography to best evaluate the renal collecting system.


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Copyright © 1969 by the American Roentgen Ray Society.