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SECONDARY CRANIOSYNOSTOSIS

CHARLES A. DUGGAN M.D.1, ELLIS B. KEENER M.D.2, and BRIT B. GAY JR. M.D.3

1 Fellow in Radiology, supported by U.S.P.H.S. Grant 5T0I HE5494-09.
2 Attending Neurosurgeon, Henrietta Egleston Hospital for Children.
3 Professor of Radiology, School of Medicine, Emory University; and Radiologist, Henrietta Egleston Hospital for Children, Atlanta, Georgia.

The literature contains many articles on primary premature craniosynostosis (PCS). There are allusions to secondary PCS and some key articles are found in which PCS is attributed to some other disease entity or considered a part of another well known syndrome. Based on a review of the literature and our own cases, we have attempted to present the many conditions associated with or considered an integral part of PCS.

The resulting craniofacial deformities secondary to PCS are numerous and variable. The pathogenesis and etiology are really not known. Therefore, no one classification will satisfy every need. Our proposed classification is presented simply to call attention to the many conditions in which PCS has been found.


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 Obstet GynecolHome page
S. A. Rasmussen, M. M. Yazdy, S. L. Carmichael, D. J. Jamieson, M. A. Canfield, M. A. Honein, and for the National Birth Defects Prevention Study
Maternal Thyroid Disease as a Risk Factor for Craniosynostosis
Obstet. Gynecol., August 1, 2007; 110(2): 369 - 377.
[Abstract] [Full Text] [PDF]


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