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PREDICTABILITY OF RED CELL VOLUME FROM RISA BLOOD VOLUME

MARTIN L. NUSYNOWITZ LTC, MC, USA, WILBUR J. STRADER III MAJ, MC, USA, and JEROME A. WALISZEWSKI

The RISA plasma label method of estimating red cell volume is technically simple, rapid, adaptable to automation, and can be performed repeatedly but has been criticized because of discrepancies in individual results when compared to Cr51 cell label methods.

Determinations in 33 patients have shown an extremely high degree of correlation between both methods (r= +0.974), attesting to the predictability of one from the other. Most of the discrepancies in results were quite small, and none was so great as to negate its clinical usefulness. The simpler RISA method of red cell volume estimation is very adequate for most clinical purposes.


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