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ORBITAL SCLEROSIS IN HISTIOCYTOSIS X

MARK E. NESBIT JR. M.D., JUSTIN J. WOLFSON M.D., STEPHEN A. KIEFFER M.D., and HAROLD O. PETERSON M.D.

A review of roentgenographic studies of the skull in 62 patients with histiocytosis X revealed 14 with orbital involvement. Five of the 14 have shown increased thickness and sclerosis of the orbital roofs, all with a similar pattern. The remaining 9 cases showed more typical lytic lesions of the roof and zygomatic arch. The occurrence of orbital sclerosis was not related to the type of therapy employed. Serial studies suggest that the sclerosis and thickening are related to healing of destructive areas within the orbital roofs.


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