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THE FISSURE SIGN: ITS MULTIPLE CAUSES

A. EVERETTE JAMES JR. M.D.1, JAMES J. CONWAY M.D.2, C. H. (JOSEPH) CHANG M.D.3, MALCOLM COOPER M.D.4, ROBERT I. WHITE M.D.5, and H. WILLIAM STRAUSS 6

1 Formerly Harvard Teaching Fellow, Massachusetts General Hospital, Boston, Massachusetts. Advanced Academic Fellow of the James Picker Foundation, recommended by the Committee on Radiology, National Academy of Science, National Research Council. Department of Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland.
2 Department of Radiology, Children’s Memorial Hospital, Chicago, Illinois.
3 Professor and Acting Chairman, Department of Radiology, West Virginia University Medical School, Morgantown, West Virginia.
4 Division of Nuclear Medicine and Environmental Medicine, Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland.
5 Scholar of James Picker Foundation, Department of Radiology, University of Minnesota, Minneapolis, Minnesota.
6 Department of Radiology, Fellow in Nuclear Medicine, Johns Hopkins Hospital, Baltimore, Maryland.

The "fissure sign" appears as a linear area of decreased radioactivity on a perfusion scan which corresponds in position and configuration to the interlobar fissure. This pattern is seen in association with pleural fluid, thickening of the interlobar fissure, chronic lung disease, and pulmonary microemboli.


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