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AN UNUSUAL ASSOCIATION OF MULTIPLE MENINGIOMAS, INTRACRANIAL ANEURYSM, AND CEREBROVASCULAR ATHEROSCLEROSIS IN TWO YOUNG WOMEN

JOHN P. JIMENEZ M.D., JOHN A. GOREE M.D., and JOSEPH C. PARKER JR. M.D.1

1 Laboratory of Pathology, New England Deaconess Hospital, Boston, Massachusetts.

An unusual association of multiple meningiomas and intracranial aneurysm with atherosclerotic ectatic changes of the cerebral arteries has been observed in 2 young women with progressive visual loss.

The relationship of these abnormalities to each other may be coincidental; however, a dysgenetic defect cannot be excluded.

The occurrence of atherosclerosis in young women is not only decidedly uncommon, but also certainly abnormal, and with these other lesions creates a peculiar syndrome.

Von Recklinghausen’s neurofibromatosis could not be established in either patient.


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