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THYROIDAL PERTECHNETATE UPTAKE IN HASHIMOTO’S DISEASE

WOLFGANG HAUSER M.D., HAROLD L. ATKINS M.D., WILLIAM C. ECKELMAN PH.D., and POWELL RICHARDS B.S.

Two conditions other than hyperthyroidism will lead to an elevation of the thyroidal pertechnetate uptake.

The first situation is in patients taking medication containing estrogens.

The second situation is in patients with chronic thyroiditis. In patients with this disorder the pertechnetate uptake was consistently higher than expected from over-all thyroid function. In 19 patients the mean pertechnetate uptake was 5.18±2.73 per cent compared to a mean of 1.69±0.77 per cent in 53 patients with nontoxic nodular goiter. This finding is of importance because it aids in the diagnosis of Hashimoto’s disease without surgery and it allows identification of individuals who may become hypothyroid in the future.


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