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PEPTIC ULCER OF THE PYLORIC REGION

MORTON G. GLICKMAN M.D., GEORGE SZEMES M.D., PETER LOEB M.D., and ALEXANDER R. MARGULIS M.D.

Of 40 patients with pyloric ulcers, 26 (65 per cent) presented a characteristic clinical syndrome consisting of atypical pain, nausea and vomiting, and weight loss.

No difference was noted in clinical presentation, course, or prognosis between ulcers limited to the pylorus and ulcers on the gastric or duodenal side of the pylorus. Furthermore, ulcers frequently appeared to migrate across the pylorus on follow-up studies. Therefore, we believe that all ulcers that involve the pylorus should be considered pyloric ulcers, regardless of extent.

Two malignant ulcers were found; one was an adenocarcinoma and the other a lymphoma. Neither could be differentiated on roentgenographic or gross pathologic examinations from benign ulcer.


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