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CHOLANGIOGRAPHIC FINDINGS IN DISEASES OF THE LIVER: A POSTMORTEM STUDY

DAVID A. LEGGE M.B., D.M.R.D., HARLEY C. CARLSON M.D., and JURGEN LUDWIG M.D.

Postmortem cholangiograms in 100 unselected cases were studied.

Generalized dilatation of the ducts occurred in cases in which there had been previous cholecystectomy. Displacement of bile ducts, with or without narrowing and dilatation, was present in cases with hepatic tumor metastases. Elongation and straightening was present in fatty livers and in 2 of 4 cases of lymphomatous involvement of the liver. In cirrhosis, the bile ducts were crowded together and displaced. Cholangiolitic hepatitis was studied in 1 case, in which the ducts were crowded, displaced, narrowed, dilated, or absent.

Most of these changes were too subtle to be of much clinical value, with the exception of the narrowing caused by large and widespread tumor metastasis of the liver and by cholangiolitic hepatitis.

Where significant changes of the intrahepatic ducts are encountered, they are likely to be the result of extensive hepatic metastases or of primary disease of the bile ducts such as carcinoma, sclerosing cholangitis, and cholangiolitic hepatitis.


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