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COMPENSATORY RENAL HYPERTROPHY

ABSENCE IN UTERO AND DEVELOPMENT IN EARLY LIFE

IGOR LAUFER M.D.1 and N. THORNE GRISCOM M.D.2

1 Chief Resident in Radiology, Beth Israel Hospital, Boston, Massachusetts; Fellow in Radiology, Harvard University, Boston, Massachusetts; Formely Affiliating Resident, Children's Hospital Medical Center, Boston, Massachusetts.
2 Radiologist, Children's Hospital Medical Center, Boston, Massachusetts; Assistant Professor of Radiology, Harvard University, Boston, Massachusetts.

Measurement of the length of the opposite kidney before and after removal of a multicystic dysplastic kidney shows that:

1. Compensatory renal hypertrophy does not develop in utero.

2. Compensatory hypertrophy develops promptly after birth.

3. Enlargement is sufficient to make total renal mass approximately normal by the age of 1frac12 years.

4. Compensatory hypertrophy probably develops whether or not the nonfunctioning kidney is removed.


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