SPLENIC ARTERIOGRAPHY IN HODGKIN'S DISEASE

A ROENTGENOLOGIC-PATHOLOGIC STUDY OF 33 CONSECUTIVE UNTREATED PATIENTS

In an attempt to evaluate the role of arteriography in predicting Hodgkin's involvement of the spleen, 33 consecutive untreated patients were studied with selective arteriography prior to laparotomy.

Splenectomy was performed within 10 days of the angiography, and in 36 per cent (12/33) Hodgkin's disease was found in the surgical specimen. The arterial and venous phases showed absence of pathologic vessels, encasement, or displacement. A nonhomogeneous tissue phase was seen in both normal and abnormal spleens. In 2 patients focal filling defects seen on tomograms obtained in conjunction with angiography corresponded to foci of disease seen in the specimen. Although the angiographic spleen size was directly related to the weight of the surgical specimen, this did not correlate with the presence of disease.

Splenic arteriography is not sufficiently sensitive or reliable to predict splenic involvement when initially staging patients with Hodgkin's disease.

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