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In 16 patients with pheochromocytoma, plain film examinations were useful in detecting and evaluating lung and bone metastases which did not seem to have a unique appearance. "Blowout" bone metastases were seen frequently and resembled bone metastases from thyroid, renal cell, and occasionally bronchogenic carcinomas.
Special roentgenologic examinations not only were helpful for locating the primary lesion but also were used to advantage in evaluating soft tissue extension, tumor recurrence, and metastatic involvement in the liver.
Radiation therapy produced no evidence of healing or recalcification in bone lesions, even in those patients who survived many years. In 9 patients treated with radiation therapy we have had 2 apparent long-term controls. We believe that in order to be effective against metastatic pheochromocytoma, radiation therapy must be delivered in doses in excess of 3,500 to 4,000 r.
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S. Sandur, A. Dasgupta, J. L. Shapiro, A. C. Arroliga, and A. C. Mehta Thoracic Involvement With Pheochromocytoma: A Review Chest, February 1, 1999; 115(2): 511 - 521. [Abstract] [Full Text] [PDF] |
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