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MALACOPLAKIA OF THE URINARY TRACT

G. B. ELLIOTT F.R.C.P. (C), F.R.C. PATH., P. J. MOLONEY F.R.C.S. (C), and J. G. CLEMENT F.R.C.P. (C)

Malacoplakia appears as dome-shaped yellow nodules which stud the surfaces of the genitourinary tract. Throughout their evolution the overlying epithelium remains intact. In early phases they simulate pyelocystitis cystica, which is usually far more discrete. The malacoplakic nodules grow to 2.5 cm. diameter in bladder and then resemble bullous cystitis, or if single they simulate tumor or endometrioma. Only isolated amyloid nodule of bladder, however, is also yellow.

As malacoplakic nodules heal, they do so individually, and have an umbilicated moon-crater appearance which is quite characteristic. Crops of lesions may appear over several years of observation. Final healing is without scarring.

The various radiologic features and cystoscopic and pathologic correlations are reviewed from studies on 5 instances.


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