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SJÖGREN-LARSSON SYNDROME WITH EPIPHYSEAL METAPHYSEAL DYSPLASIA

M. B. OZONOFF M.D. and JOHN A. OGDEN M.D.

A 9 year old girl with the clinical findings of Sjögren-Larsson syndrome (mental retardation, short stature, spasticity, and congenital ichthyosis) was found to have a mild epiphyseal and metaphyseal dysplasia.

Retarded bone maturation, increased interpediculate distance in the lower spine, and significant widening of the pubic symphysis were also present.

A specific epiphyseal and metaphyseal dysplasia has not been previously illustrated in this condition, and the incidence of such in these patients is not now known.


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